Founded in 2011 by Brendan Dugan and currently located in NY’s East village, Karma represents a diverse roster of multi-generational artists. The gallery hosts twenty exhibitions each year, many of which are accompanied by Karma-published monographs and artist books. In 2018, Karma opened its standalone bookstore that presents artist books and rare ephemera alongside the gallery's publications.
Works by the gallery’s artists are featured in numerous public collections including the Metropolitan Museum of Art, New York; Smithsonian American Art Museum, Washington D.C.; Stedelijk Museum Amsterdam; and Hammer Museum, Los Angeles, among others. In addition to its two gallery spaces, Karma opened a third gallery space in July of 2021.